Jesus puts the anxious questions into words so His hearers can hear how they sound. "Therefore" ties this command to everything He has just said about the birds, the cubit, the lilies, and the grass. The three questions match the three worries He named at the start: what to eat, what to drink, and what to put on (Matthew 6:25). Gill explains that Jesus means worry about the future: "for it is lawful to take proper care and thought for present food, drink, and raiment; but not to be anxiously concerned for futurity."

Jesus answers the three questions with two facts. These are the things "the Gentiles seek," and "your heavenly Father knoweth that ye have need of all these things" (Matthew 6:32). Then He gives His hearers a better aim: "But seek ye first the kingdom of God, and his righteousness; and all these things shall be added unto you" (Matthew 6:33). He closes, "Take therefore no thought for the morrow" (Matthew 6:34).

"Wherewithal" means "with what." The ESV simplifies it to "What shall we wear?" All three worried questions are spoken in the first person plural, "we." "Take no thought" again translates merimnao, to be anxious.

The "Gentiles" in Matthew 6:32 are the nations outside Israel. Gill explains why they chased these things: "These knew not God, nor acknowledged his providence; the greater part of them thought, that the soul perished with the body."

These are everyday questions, and Jesus does not mock them. He answers them with a Father who already knows (Matthew 6:32). Earlier in the same sermon He said, "your Father knoweth what things ye have need of, before ye ask him" (Matthew 6:8), and taught His disciples to pray, "Give us this day our daily bread" (Matthew 6:11). The issue is not whether these needs are real, but to whom we bring them.

Matthew Henry puts the comfort warmly: "your God knows them; and he is your Father that loves you and pities you." Jesus is not taking away concern for daily needs; He is giving it a home in prayer, so the heart is free to seek God's kingdom first.